ULTRASTRUCTURE OF CANINE RENAL HOMOGRAFTS

The Ultrastructure of Canine Cutaneous Papilloma1

The fine structure of cutaneous papilloma in the dog was studied in two biopsy specimens fixed in formalin, postfixed in osmium tetroxide, and processed through the Epon embedding technic. The most prominent changes were found in the nuclei of epidermal cells, especially in the granular layer of neoplastic fronds. The affected nuclei contained inclusion bodies in various stages of morphologic d...

Selective Lymphopenia by Use of Intralymphatic 198-au and Splenectomy. Immunosuppressive Action on Rejection of Canine Renal Homografts.

A Technique for Use of Adult Renal Homografts in Children.

RENAL TRANSPLANTATION as originally described by Kiiss and later refined by Murray and Harrison has proved to be an effective operation from a technical point of view. The donor kidney is placed in the contralateral iliac fossa of the recipient, and thereby the anteroposterior relations of the hilar structures are reversed. The renal vessels are attached to the end and side, respectively, of th...

The fate of failed renal homografts retained after retransplantation.

IN MANY TRANSPLANTATION CENTERS, it has been considered obligatory to remove failed renal homografts before, or at, retransplantation, since such grafts have been regarded as a potential hazard to the patient. At our institution, this routine has, in the last years, been applied only to grafts which failed in the immediate postoperative period and which, consequently, were considered infarcted....

Modification of established rejection of canine kidney and liver homografts with antilymphocyte gamma-G globulin.

T ability of h,',rologo"" antilymphocyte serum (ALS) or its globulin derivative (ALG) to mitigate or even prevent homograft rejection is well known. In early investigations with skin homotransplantation in inbred rodents, it was shown that ALS given even several days after arrival of the homograft resulted in definite prolongation of transplant survival,4,7 This communication concerns an extens...